Yafei Wang

This study develops a multicellular agent-based model to simulate nanoparticle interactions in cancer therapy and evaluates how pharmacokinetic parameters and therapeutic strategies affect tumor dynamics.

The paper introduces a framework for mathematical modeling of multicellular systems using interpretable cell behavior rules derived from biological knowledge and multi-omics data.

This study uses multi-model simulations to show how liver parenchyma biomechanics influence metastatic tumor growth and dormancy.

Open-source agent-based PhysiCell model of SARS-CoV-2 infection in lung epithelium; version 5 clears virus in about 6 days in simulation, and delayed T cell arrival increases epithelial loss.