Daraxonrasib (RMC-6236) is an effective targeted therapy for RAS-mutant neuroblastoma
Ronald D. Hill, Krista M. Dalton, Richard Kurupi, Jamie M. Slaughter, Jane Roberts, Yanli Xing, Victor Kehinde, Kun Zhang, Bin Hu, Vita Kraskauskiene, Madelyn R. Lorenz, Jennifer E. Koblinski, Mikhail G. Dozmorov, Konstantinos V. Floros, Anthony C. Faber
This study shows that Daraxonrasib (RMC-6236) effectively targets RAS-mutant neuroblastoma by inhibiting MAPK signaling and enhancing cell death.
bioRxiv · Feb 20, 2026 · PreprintCancer Biology