DNA damage causes ATM-dependent heterochromatin loss leading to nuclear softening, blebbing, and rupture
Nebiyat Eskndir, Manseeb Hossain, Marilena L. Currey, Mai Pho, Yasmin Berrada, Katie Y. Lin, Gianna Manning, Kelsey Prince, Andrew D. Stephens
This study shows DNA damage reduces heterochromatin via ATM, leading to nuclear softening, blebbing, and rupture in MEF cells.
Molecular Biology of the Cell · Dec 20, 2024Peer-reviewedCell Biology