HIF1α controls adipose tissue growth through metabolic rechanneling
Chaonan Zhu, Meiqian Wu, Duc Minh Pham, Yue Wang, Arka Provo Das, Yi-Jie Mao, Peter Mirtschink, Ting Yuan, Jaya Krishnan
This study shows that HIF1α is essential for adipose tissue growth under normal conditions and in response to high-fat diets, by rechanneling metabolic intermediates into lipid synthesis.
bioRxiv · May 28, 2024 · PreprintCell Biology