Author

Chaonan Zhu

Goethe University FrankfurtORCID 0000-0002-8337-8484Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Arka Provo Das· 3 shared Jaya KrishnaniD· 3 shared Meiqian WuiD· 3 shared Ting YuaniD· 3 shared Duc Minh PhamiD· 2 shared Maria Duda· 2 shared Peter MirtschinkiD· 2 shared Stefanie DimmeleriD· 2 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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3 shared papersCell Biology

Arka Provo Das

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Human heart organoids reveal a regenerative strategy for mitochondrial disease

Minh Duc Pham, Arka Provo Das, Yue Wang, Despina Stefanoska, Ting Yuan, Chaonan Zhu, Meiqian Wu, Alfredo Cabrera‐Orefice, Luka Nicin, Shane Bell, Mathias Langner, U. Gärtner, Oliver M. Russell, Jonathan Ward, Mirko Peitzsch, , Jaya Krishnan

The paper uses human heart organoids to model mitochondrial disease and identifies a drug that improves mitochondrial function and tissue contractility.

bioRxiv · Dec 21, 2025 · PreprintCell Biology

HIF1α controls adipose tissue growth through metabolic rechanneling

Chaonan Zhu, Meiqian Wu, Duc Minh Pham, Yue Wang, Arka Provo Das, Yi-Jie Mao, Peter Mirtschink, Ting Yuan, Jaya Krishnan

This study shows that HIF1α is essential for adipose tissue growth under normal conditions and in response to high-fat diets, by rechanneling metabolic intermediates into lipid synthesis.

bioRxiv · May 28, 2024 · PreprintCell Biology

CVD-associated SNPs with regulatory potential drive pathologic non-coding RNA expression

Chaonan Zhu, Nina Baumgarten, Meiqian Wu, Yue Wang, Arka Provo Das, Jaskiran Kaur, Fatemeh Behjati Ardakani, Thanh Thuy Duong, Duc Minh Pham, Maria Duda, Stefanie Dimmeler, Ting Yuan, Marcel H. Schulz, Jaya Krishnan

The paper identifies regulatory SNPs linked to CVDs and shows their impact on non-coding RNA expression and cardiac function in disease models.

Human Genomics · Jul 25, 2023Peer-reviewedGenomics