Author

Yifan Sheng

Center for Excellence in Brain Science and Intelligence Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:snRNA-seq· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Baoxing Dong· 1 shared Binshi Bo· 1 shared Biyu ReniD· 1 shared Bo WangiD· 1 shared Chan Xu· 1 shared Chenxiang XiiD· 1 shared Chuanyu LiuiD· 1 shared Chun Xie· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperDevelopmental Biology

Baoxing Dong

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2 papers

Recent·Most cited

Modeling Post-Gastrula Development via Bidirectional Pluripotent Stem Cells

Kuisheng Liu, Zihui Yan, Dandan Bai, Rui Jiang, Yan Bi, Xiangjun Ma, Jiani Xiang, Yifan Sheng, Baoxing Dong, Zhiyuan Ning, Shanru Yi, Yingdong Liu, Xinyi Lei, Yanping Jia, Yan Zhang, , Wenqiang Liu

This study develops bidirectional pluripotent stem cells (BPSCs) capable of generating both trophoblast and epiblast lineages, enabling the recapitulation of post-gastrula development in vitro and in vivo.

Cell Research · Aug 29, 2025Peer-reviewedDevelopmental Biology

Spatially resolved molecular and cellular atlas of the mouse brain

Lei Han, Zhen Liu, Zehua Jing, Yuxuan Liu, Huizhong Chang, Junjie Lei, Yujie Peng, Kexin Wang, Yuanfang Xu, Wei Liu, Zihan Wu, Qian Li, Xiaoxue Shi, Mingyuan Zheng, He Wang, , Sha Liao

The paper creates a high-resolution spatial transcriptomic atlas of the mouse brain using snRNA-seq and Stereo-seq, identifying new cell clusters, region-specific genes, and transcription factor regulons.

bioRxiv · Dec 3, 2023 · PreprintNeuroscience