Assessment of drive efficiency and resistance allele formation of a homing gene drive in the mosquito Aedes aegypti
Xiaozhen Yang, Xuejiao Xu, Yixian Chen, Jiajia Wei, Wanting Huang, Songqing Wu, Jackson Champer, Junxiang Wang
This study evaluates the efficiency and resistance allele formation of two CRISPR/Cas9-based gene drives in Aedes aegypti, finding one drive achieves super-Mendelian inheritance rates.
bioRxiv · Sep 24, 2024 · PreprintGenetics