ImmunologybioRxivPreprint
A BCG toxic effector induces mitochondrial DNA compaction to refrain protective immunity
Cheng Peng, Chen Qiu, Jingping Huang…·Baoxue Ge
This study shows that BCG effector PE18 induces mitochondrial DNA compaction to suppress trained immunity and protective immunity against Mtb.
DOI 10.1101/2025.11.09.687409