A multifunctional polyketide synthase in nematodes produces divergent families of signaling molecules that control different developmental arrests
Kevin Mai, Chi‐Su Yoon, Dilip V. Prajapati, Yuelan Li, Rongrong Yu, Hanh Witte, Subhradeep Bhar, Likui Feng, Elijah Abraham, Matthew T. Gordon, Surasree Rakshit, Fnu Priya, Ralf J. Sommer, Rebecca A. Butcher
This paper identifies a multifunctional PKS-NRPS hybrid in nematodes that produces diverse signaling molecules controlling different developmental arrests.
bioRxiv · May 29, 2026 · PreprintBiochemistry