Yuguo Lei

Collagen Nanofiber Reinforced Alginate Hydrogel Tube Microbioreactors for Cell Culture

This paper introduces collagen-alginate hybrid hydrogel microtubes (ColAlgTubes) that enhance cell culture efficiency by improving adhesion, mechanical stability, and scalability.

Alginate-Coated Collagen Hydrogel Tubes for Scalable Cell and Biotherapeutic Particle Manufacturing

This paper introduces AlgColTubes, alginate-coated collagen hydrogel tubes that improve scalability and reduce adhesion in cell and biotherapeutic particle manufacturing.

Alternating 2D and 3D Culture Reduces Cell Size and Extends the Lifespan of Placenta-Derived MSCs

This paper shows that alternating 2D and 3D culture reduces cell size and extends the lifespan of placenta-derived MSCs while preserving their immunomodulatory function.

Scalable Culture of Mammalian Cells in RGD Peptide-Modified Alginate Hydrogel Microtubes

This study develops AlgTubes, RGD peptide-modified alginate hydrogel microtubes, to enable scalable culture of myoblasts and adipocytes for cultured meat, achieving higher cell densities than traditional bioreactors.

Identification of RNA-based cell-type markers for the stem cell manufacture system with a statistical scoring function

The paper identifies RNA-based cell-type markers for stem cell manufacture using a statistical scoring function and validates them with deep learning and simulated data.