Author

Yakun Yang

Pennsylvania State UniversityORCID 0000-0002-4772-4263Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:clustering· 2 Research Focus:development & morphogenesis· 2 Assay:organoid / primary culture· 2 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Xinran WuiD· 3 shared Yuguo Lei· 3 shared Aijun WangiD· 2 shared Shue WangiD· 2 shared Wuqiang ZhuiD· 2 shared Aziza P. ManceuriD· 1 shared Cheng DongiD· 1 shared Han LiiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersBioengineering

Xinran WuORCID

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Author profile →

3 papers

Recent·Most cited

Collagen Nanofiber Reinforced Alginate Hydrogel Tube Microbioreactors for Cell Culture

Xinran Wu, Yakun Yang, Ying Pan, Yong Wang, Xiaojun Lance Lian, Cheng Dong, Shue Wang, Aijun Wang, Wuqiang Zhu, Wansheng Liu, Yuguo Lei

This paper introduces collagen-alginate hybrid hydrogel microtubes (ColAlgTubes) that enhance cell culture efficiency by improving adhesion, mechanical stability, and scalability.

Frontiers in Bioengineering and Biotechnology · Jun 19, 2026Peer-reviewedBioengineering

Alginate-Coated Collagen Hydrogel Tubes for Scalable Cell and Biotherapeutic Particle Manufacturing

Xinran Wu, Ying Pan, Yakun Yang, Li Han, Yong Wang, Aziza P. Manceur, Yuguo Lei

This paper introduces AlgColTubes, alginate-coated collagen hydrogel tubes that improve scalability and reduce adhesion in cell and biotherapeutic particle manufacturing.

bioRxiv · Jun 2, 2026 · PreprintBioengineering

Alternating 2D and 3D Culture Reduces Cell Size and Extends the Lifespan of Placenta-Derived MSCs

Ying Pan, Han Li, Yakun Yang, Xinran Wu, Aijun Wang, Liangqi Xie, Wuqiang Zhu, Shue Wang, Yuguo Lei

This paper shows that alternating 2D and 3D culture reduces cell size and extends the lifespan of placenta-derived MSCs while preserving their immunomodulatory function.

bioRxiv · May 20, 2025 · PreprintBioengineering