Single-cell time-series mapping of cell fate trajectories reveals an expanded developmental potential for human PSC-derived distal lung progenitors
Killian Hurley, Jun Ding, Carlos Villacorta-Martín, Michael J. Herriges, Anjali Jacob, Marall Vedaie, Konstantinos–Dionysios Alysandratos, Yuliang L. Sun, Chieh Hubert Lin, Rhiannon B. Werder, Andrew A. Wilson, Aditya Mithal, Gustavo Mostoslavsky, Ignacio S. Caballero, Susan H. Guttentag, , Darrell N. Kotton
The paper maps cell fate trajectories of human PSC-derived distal lung progenitors using scRNA-seq and identifies developmental plasticity regulated by Wnt signaling.
bioRxiv · Sep 26, 2019 · PreprintDevelopmental Biology