Author
Agricultural Genomics Institute at ShenzhenORCID 0000-0001-8259-0275Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Jiaoyang Liao, Hongling Zhang, Shuanghong Chen…·Yuming Lu
This paper develops hpABE5.20, a base editor with improved precision and reduced off-target effects through sequential amino acid mutagenesis and AI-based structural prediction.
Jiaying Huang, Qiupeng Lin, Hongyuan Fei…·Caixia Gao
The paper uses AlphaFold2 to cluster deaminase proteins by structure, discovers new properties, and develops improved base editors for therapeutic and agricultural use.
Yanxia Gao, Kailun Fang, Zixiang Yan…·Hui Yang
The paper develops an optimized AAV-based labeling system for Muller glia in mice, showing improved efficiency and specificity compared to existing methods.
Yalan Yang, Jinmin Lian, Bingkun Xie…·Zhonglin Tang
The paper presents a high-quality phased chromosome-scale genome assembly of a Chinese indigenous pig and identifies genetic differences between this breed and Duroc pigs.
Erwei Zuo, Yidi Sun, Wei Wu…·Hui Yang
This study compares off-target single nucleotide variants (SNVs) from CRISPR-Cas9 and base editing (BE3) in mouse embryos using the GOTI method, finding BE3 causes significantly more SNVs.