Author

Yuping Tan

Sichuan University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Assay:protein structure· 1 Organism:yeast· 1

Frequent Co-Authors

Da JiaiD· 2 shared Qingxiang SuniD· 2 shared Aiping Tong· 1 shared Jinhan Zhou· 1 shared Qiao Zhou· 1 shared Xiaodong Sun· 1 shared Xiaofei Shen· 1 shared Yuling Li· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMolecular Biology

Da JiaORCID

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2 papers

Recent·Most cited

Plumbagin and oridonin reveal new CRM1 binding sites and NES-binding groove features

Yuqin Lei, Yuling Li, Yuping Tan, Da Jia, Qingxiang Sun

This study identifies new CRM1 binding sites and structural features of the NES-binding groove using plumbagin and oridonin, revealing potential mechanisms for CRM1 inhibition.

bioRxiv · Aug 5, 2020 · PreprintMolecular Biology

Destabilization of Ran C-terminus promotes GTP loading and occurs in multiple Ran cancer mutations

Yuqing Zhang, Jinhan Zhou, Yuping Tan, Qiao Zhou, Aiping Tong, Xiaofei Shen, Da Jia, Xiaodong Sun, Qingxiang Sun

This study shows that destabilizing the C-terminus of Ran promotes GTP loading and is associated with cancer mutations, suggesting a new mechanism for cellular transformation and potential drug targets.

bioRxiv · Apr 20, 2018 · PreprintBiochemistry