Anionic Lipid Trafficking and Cell Mechanics RegulateMembrane Electrical Potential in Non-Excitable Tissue Cells
Zhuoxu Ge, Qin Ni, Yuqing Yan, Yufei Wu, Bishwa Ranjan Si, Jinyu Fu, Dingchang Lin, Konstantinos Konstantopoulos, Yizeng Li, Sean X. Sun
This study shows that non-excitable cells have spatially varying membrane potentials linked to anionic lipid distribution and mechanical factors, challenging the traditional view of membrane potential regulation.
bioRxiv · Nov 25, 2025 · PreprintBiophysics