Dingchang Lin

This paper introduces RGRs, genomic repeats that enable high-resolution single-cell molecular recording, validated in live mice for long-term gene activity tracking.

This paper introduces GEMINI, a tool that records cellular activity histories with high temporal resolution, and demonstrates its application in tracking transcriptional changes and inflammation dynamics in vivo.

This study shows that non-excitable cells have spatially varying membrane potentials linked to anionic lipid distribution and mechanical factors, challenging the traditional view of membrane potential regulation.

The paper develops a protein-based ticker tape system to record neural activation histories with high temporal resolution.

The paper identifies neuroprotective genes in retinal ganglion cells by analyzing their resilience to injury using single-cell RNA-seq and functional assays.