Author
Johns Hopkins UniversityORCID 0000-0002-0738-1817Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Qin Ni, Jingyao Ma, Jinyu Fu, Ladaisha T. Thompson, Zhuoxu Ge, D. Sharif, Yining Zhu, Hai-Quan Mao, Jude M. Phillip, Sean X. Sun
This study quantitatively investigates how different nanoplastics associate with and affect diverse cell types, revealing cell-type-dependent impacts on proliferation and motility.
bioRxiv · Apr 7, 2026 · PreprintCell Biology
Melvin Li, Chenille A McCullum, Louis T.A. Rolle, Qin Ni, Zhuoxu Ge, Sean X. Sun, Kenneth J. Pienta, Sarah R. Amend
This study shows that cancer cells surviving cisplatin chemotherapy increase OMA1 activity and mitochondrial fragmentation to resist oxidative stress.
Scientific Reports · Jan 6, 2026Peer-reviewedCancer Biology
Zhuoxu Ge, Qin Ni, Yuqing Yan, Yufei Wu, Bishwa Ranjan Si, Jinyu Fu, Dingchang Lin, Konstantinos Konstantopoulos, Yizeng Li, Sean X. Sun
This study shows that non-excitable cells have spatially varying membrane potentials linked to anionic lipid distribution and mechanical factors, challenging the traditional view of membrane potential regulation.
bioRxiv · Nov 25, 2025 · PreprintBiophysics
Qin Ni, Zhuoxu Ge, Anindya Sen, Yufei Wu, Jinyu Fu, Alice Amitrano, Nitish Srivastava, Κωνσταντίνος Κωνσταντόπουλος, Sean X. Sun
This study identifies a chemical compensation mechanism in cells responding to mechanical stimuli, revealing non-monotonic changes in volume and pH mediated by PI3K/Akt and MAPK/ERK pathway interactions.
Proceedings of the National Academy of Sciences · Nov 7, 2025Peer-reviewedBiophysics
Jinyu Fu, Qin Ni, Yufei Wu, Anoushka Gupta, Zhuoxu Ge, Hongru Yang, Yasin Afrida, Ishan Barman, Sean X. Sun
The paper investigates cell mass density (CMD) dynamics after osmotic shock and finds CMD recovers monotonically through coordinated protein synthesis and volume growth, with NHE playing a regulatory role.
Science Advances · Aug 27, 2025Peer-reviewedBiophysics