Author

Yuri A. Abramov

Kurchatov Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Molecular Biology· 4 Genomics· 1

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Organism:Drosophila· 5 Approach:experimental assay· 5 Research Focus:cell type annotation· 3 Research Focus:gene regulatory network inference· 3 Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Research Focus:protein structure prediction· 2

Frequent Co-Authors

Elena A. MikhalevaiD· 4 shared Natalia V. AkulenkoiD· 3 shared Sergey A LavroviD· 3 shared Vladimir A. GvozdeviD· 3 shared Aleksei S. ShatskikhiD· 2 shared Elena A. FefelovaiD· 2 shared Galina L. KoganiD· 2 shared Mikhail S. KlenoviD· 2 shared

Activity by Year

2018-2025 · peak 2/yr

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10 top collaborators · 33 mutual co-author links

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4 shared papersMolecular Biology

Elena A. MikhalevaORCID

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5 papers

Recent·Most cited

Piwi and piRNAs repress transcription of aberrant rRNA genes containing retrotransposon fragments

Elena A. Fefelova, Aleksei S. Shatskikh, Elena A. Mikhaleva, Yuri A. Abramov, Sergey A Lavrov, Сергей Анатольевич Пирогов, Valentin A. Poltorachenko, Artem A. Ilin, Phillip D. Zamore, Mikhail S. Klenov

The paper shows that Piwi and piRNAs repress transcription of defective rRNA genes with truncated retrotransposon insertions in Drosophila ovaries, preventing aberrant rRNA accumulation.

bioRxiv · Apr 30, 2025 · PreprintMolecular Biology

A study of the expression of germline-specific paralogs of the ubiquitously expressed NAC complex revealed their association with centrosomes

Elena A. Mikhaleva, Natalia V. Akulenko, Oxana M. Olenkina, Yuri A. Abramov, Sergey A Lavrov, Thoomas A. Leinsoo, Galina L. Kogan, Vladimir A. Gvozdev

The paper investigates germline-specific NAC paralogs in Drosophila, showing their association with centrosomes and their role in proteostasis and fertility.

bioRxiv · Dec 12, 2022 · PreprintMolecular Biology

Role of Udd protein and heterochromatin in transcriptional selection of individual rRNA genes in the Drosophila germline

Elena A. Fefelova, I. M. Pleshakova, Elena A. Mikhaleva, Сергей Анатольевич Пирогов, Valentin A. Poltorachenko, Yuri A. Abramov, Daniil D. Romashin, Aleksei S. Shatskikh, Roman S. Blokh, Vladimir A. Gvozdev, Mikhail S. Klenov

The paper investigates how Udd protein and heterochromatin regulate rRNA gene transcription in Drosophila germline, showing Udd's role in distinguishing active from silent rDNA units.

Nucleic Acids Research · Dec 14, 2021Peer-reviewedMolecular Biology

Detection of the germline specific NAC protein paralog enriched by intrinsically disordered regions in Drosophila melanogaster

Galina L. Kogan, Elena A. Mikhaleva, Oxana M. Olenkina, Sergei S. Ryazansky, Oxana V. Galzitskaya, Yuri A. Abramov, Toomas A. Leinsoo, Natalia V. Akulenko, Vladimir A. Gvozdev

The paper identifies a germinal cell-specific NAC paralog in Drosophila with expanded intrinsically disordered regions and shows it can suppress the lethal effect of losing the ubiquitous NAC-β subunit.

bioRxiv · Mar 9, 2021 · PreprintMolecular Biology

Key role of piRNAs in telomeric chromatin maintenance and telomere nuclear positioning in Drosophila germline

Elizaveta Radion, Valeriya Morgunova, Sergei S. Ryazansky, Natalia V. Akulenko, Sergey A Lavrov, Yuri A. Abramov, Pavel A. Komarov, S. I. Glukhov, Ivan A. Olovnikov, Alla I. Kalmykova

This study shows that piRNAs are essential for telomere chromatin maintenance and nuclear positioning in Drosophila germline, with implications for heterochromatic component stability.

Epigenetics & Chromatin · Jul 12, 2018Peer-reviewedGenomics