Efficacy of Tumor Treating Fields (TTFields) in triple negative breast cancer cells and synergy with PARP inhibitor talazoparib
Maryam Ghandali, Praveen R. Srinivasan, Shengliang Zhang, Yutong Xia, Eric T. Wong, Clark C. Chen, Robert William Sobol, Stephanie L. Graff, Lanlan Zhou, Benedito A. Carneiro, Yaara Porat, Moshe Giladi, Naama Flint-Brodsly, Wafik S. El‐Deiry
This study shows TTFields increase p21 expression and induce cell death in TNBC cells, with enhanced effects when combined with talazoparib.
bioRxiv · Oct 12, 2026 · PreprintCancer Biology