Author

Praveen R. Srinivasan

Brown UniversityORCID 0000-0002-9548-4786Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cancer Biology· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:human· 3 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Wafik S. El‐DeiryiD· 4 shared Connor PurcelliD· 2 shared Maximilian P. Pinho-SchwermanniD· 2 shared Shengliang ZhangiD· 2 shared William J. MacDonaldiD· 2 shared Benedito A. CarneiroiD· 1 shared Clark C. CheniD· 1 shared Elizabeth C. Ding· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersCancer Biology

Wafik S. El‐DeiryORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Efficacy of Tumor Treating Fields (TTFields) in triple negative breast cancer cells and synergy with PARP inhibitor talazoparib

Maryam Ghandali, Praveen R. Srinivasan, Shengliang Zhang, Yutong Xia, Eric T. Wong, Clark C. Chen, Robert William Sobol, Stephanie L. Graff, Lanlan Zhou, Benedito A. Carneiro, Yaara Porat, Moshe Giladi, Naama Flint-Brodsly, Wafik S. El‐Deiry

This study shows TTFields increase p21 expression and induce cell death in TNBC cells, with enhanced effects when combined with talazoparib.

bioRxiv · Oct 12, 2026 · PreprintCancer Biology

Integrated stress response activation in combination PG3 and cisplatin-treated TP53-mutated head and neck squamous carcinoma cells induces potent apoptotic response

Xiaobing Tian, Praveen R. Srinivasan, Wafik S. El‐Deiry

This study shows that combining PG3 with cisplatin enhances apoptosis in TP53-mutated HNSCC cells through ISR activation and ATF4 regulation.

bioRxiv · Sep 23, 2026 · PreprintCancer Biology

ITGB6 inhibition stimulates anti-tumor responses in immunocompetent mouse models of head & neck squamous cell carcinoma and pancreatic adenocarcinoma

William J. MacDonald, Praveen R. Srinivasan, Maximilian P. Pinho-Schwermann, Shengliang Zhang, Vida Tajiknia, Connor Purcell, Jillian Strandberg, Wafik S. El‐Deiry

This study shows that inhibiting ITGB6 enhances anti-tumor immune responses in mouse models of head and neck and pancreatic cancers, with potential for combination immunotherapy.

bioRxiv · Apr 18, 2024 · PreprintCancer Biology

Neuroendocrine Prostate Cancer Drivers SOX2 and BRN2 Confer Differential Responses to Imipridones ONC201, ONC206, and ONC212 in Prostate Cancer Cell Lines

Connor Purcell, Praveen R. Srinivasan, Maximilian P. Pinho-Schwermann, William MacDonald, Elizabeth C. Ding, Wafik S. El‐Deiry

This study investigates whether neuroendocrine differentiation (NED) affects sensitivity to imipridones ONC201 and ONC206 in prostate cancer cell lines, finding differential responses based on SOX2 and BRN2 overexpression.

American Journal of Translational Research · Jan 1, 2024Peer-reviewedCancer Biology