Author

Z. Baker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 4

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 4 Approach:statistical model· 3 Assay:whole-genome sequencing· 3 Organism:multiple species· 2 Approach:comparative / phylogenetic analysis· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

M. Przeworski· 4 shared M. Schumer· 3 shared A. C. Tzika· 1 shared C. Hoge· 1 shared C. Holland· 1 shared C. R. Hoge· 1 shared G. G. Rosenthal· 1 shared G. Sella· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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4 shared papersEvolutionary Biology

M. Przeworski

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4 papers

Recent·Most cited

Patterns of recombination in snakes reveal a tug of war between PRDM9 and promoter-like features

C. R. Hoge, M. de Manuel, M. Mahgoub, N. Okami, Z. L. Fuller, S. Banerjee, Z. Baker, M. Mcnulty, P. Andolfatto, T. S. Macfarlan, M. Schumer, A. C. Tzika, M. Przeworski

The study analyzes recombination patterns in corn snakes to show that both PRDM9 and promoter-like features influence recombination, revealing a competitive interaction between these mechanisms.

bioRxiv · Jul 11, 2023Evolutionary Biology

Down the Penrose stairs: How selection for fewer recombination hotspots maintains their existence

Z. Baker, M. Przeworski, G. Sella

The paper models how PRDM9's role in coupling DSB formation and repair drives the evolution of fewer, stronger recombination hotspots.

bioRxiv · Sep 27, 2022Evolutionary Biology

PRDM9 losses in vertebrates are coupled to those of paralogs ZCWPW1 and ZCWPW2

M. I. A. Cavassim, Z. Baker, C. Hoge, M. Schierup, M. Schumer, M. Przeworski

The paper identifies genes coevolving with PRDM9 across vertebrates, suggesting ZCWPW1 and ZCWPW2 as key interactors in meiotic recombination.

bioRxiv · Jun 8, 2021Evolutionary Biology

Repeated losses of PRDM9-directed recombination despite the conservation of PRDM9 across vertebrates

Z. Baker, M. Schumer, Y. Haba, L. Bashkirova, C. Holland, G. G. Rosenthal, M. Przeworski

The paper identifies PRDM9 orthologs across 225 vertebrate species and finds repeated losses of PRDM9-directed recombination despite its conservation, linking complete orthologs to rapid evolution of binding affinity.

eLife · Jun 6, 2017Peer-reviewedEvolutionary Biology