Targeting the artemisinin resistant malaria by repositioning of the anti-Hepatitis C Virus drug Alisporivir
A. Chaurasiya, S. Garg, Z. e. Anam, G. Kumari, N. Joshi, J. Kumari, J. Singhal, N. Singh, S. Kaushik, A. Kaur, n. Dubey, P. Srivastava, M. Marothia, M. Kumar, G. Das, , A. Ranganathan
This study repositions Alisporivir, an anti-Hepatitis C drug, as a potential treatment for artemisinin-resistant malaria by targeting PfCyP-19B, which is overexpressed in resistant parasites.
bioRxiv · Jan 8, 2021 · PreprintMicrobiology