Author

P. Srivastava

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioengineering· 3 Microbiology· 2 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 7 Approach:experimental assay· 5 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:development & morphogenesis· 2 Research Focus:drug response / drug discovery· 2 Research Focus:trajectory inference· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. Chaurasiya· 2 shared A. Ranganathan· 2 shared J. Singhal· 2 shared M. Marothia· 2 shared N. Singh· 2 shared S. Kaushik· 2 shared S. Singh· 2 shared A. Awada· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

A. Chaurasiya

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Identification of merozoite secreted repertoire and immuno-pharmacological inhibition of a novel host-parasite interaction to block malarial infection

N. Singh, A. Munjal, G. Kunari, S. Kaushik, A. K. Kahlon, S. Gupta, A. Chaurasiya, Z.-e.- Anam, M. k. Maurya, P. Srivastava, J. Singhal, M. Marothia, P. Joshi, R. Jain, D. A. B. Rex, , S. Singh

This study identifies the secretory repertoire of Plasmodium merozoites and discovers a peptide that disrupts a key host-parasite interaction, blocking malarial infection.

bioRxiv · Apr 15, 2023 · PreprintMicrobiology

Motile Living Biobots Self-Construct from Adult Human Somatic Progenitor Seed Cells

G. Gumuskaya, P. Srivastava, B. G. Cooper, H. Lesser, B. Semegran, S. Garnier, M. Levin

The paper demonstrates that adult human somatic cells can self-construct into motile biobots with diverse behaviors and tissue repair capabilities without genetic modification.

bioRxiv · Aug 4, 2022Bioengineering

Linking collective migration/growth to differentiation boosts global shaping of the transcriptome and exhibits a grasshopper effect for driving maturation

O. Ogoke, D. Guiggey, A. Chiang, S. Thompson, T. H. A. Nguyen, D. Berke, C. Ott, A. Kalinousky, C. Shamul, P. Chen, S. Ross, Z. Chen, P. Srivastava, C. Gaughan, S. D. Mahajan, , N. Parashurama

The paper links collective migration to differentiation in hPSC-derived hepatocytes, showing a significant increase in maturation through a deep-learning gene circuit.

bioRxiv · Jul 24, 2022 · PreprintBioengineering

Defined microenvironments trigger in vitro gastrulation in human pluripotent stem cells

P. Srivastava, S. Romanazzo, J. Ireland, S. Nemec, T. G. Molley, P. Jayathilaka, E. Pandzic, A. Yeola, V. Chandrakanthan, J. Pimanda, K. Kilian

This study shows that microconfinement of pluripotent stem cells on hydrogels triggers gastrulation-like events without exogenous factors, leading to primitive streak formation and lineage specification.

bioRxiv · Oct 28, 2021Bioengineering

Targeting the artemisinin resistant malaria by repositioning of the anti-Hepatitis C Virus drug Alisporivir

A. Chaurasiya, S. Garg, Z. e. Anam, G. Kumari, N. Joshi, J. Kumari, J. Singhal, N. Singh, S. Kaushik, A. Kaur, n. Dubey, P. Srivastava, M. Marothia, M. Kumar, G. Das, , A. Ranganathan

This study repositions Alisporivir, an anti-Hepatitis C drug, as a potential treatment for artemisinin-resistant malaria by targeting PfCyP-19B, which is overexpressed in resistant parasites.

bioRxiv · Jan 8, 2021 · PreprintMicrobiology

HGF-induced activation of NEPHRIN and NEPH1 serves as a novel mechanism for recovery of podocytes from injury

A. K. Solanki, P. Srivastava, E. Arif, C. M. Furcht, B. Rahman, P. Wen, A. Singh, L. B. Holzman, W. R. Fitzgibbon, G. Lobo, J. H. Lipschutz, S.-H. Kwon, Z. Han, M. J. Lazzara, D. Nihalani

This study identifies HGF as a ligand that activates NEPHRIN and NEPH1 through direct binding, promoting podocyte recovery from injury.

bioRxiv · May 4, 2020 · PreprintCell Biology

Septins disruption controls tumor growth and enhances efficacy of Herceptin

R. K. Singh, K. K. Kim, N. Khazan, R. B. Rowswell_Turner, C. Laggner, A. Jones, P. Srivastava, V. Hovanesian, L. Lamere, T. Conley, R. Pandita, C. Baker, J. R. Myers, E. Prichett, A. Awada, , R. Moore

The paper develops UR214-9, a compound that disrupts septin filaments in cancer cells, inhibiting growth of HER2+ tumors and enhancing Herceptin efficacy.

bioRxiv · Feb 19, 2020 · PreprintCancer Biology