Author

Z. Sadouki

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. A. Witney· 1 shared F. Kloprogge· 1 shared J. Ortiz Canseco· 1 shared K. Kipper· 1 shared L. Phee· 1 shared N. Stoker· 1 shared T. D. McHugh· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. A. Witney

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1 paper

Recent·Most cited

Understanding emergence of antimycobacterial dose dependent resistance.

F. Kloprogge, J. Ortiz Canseco, L. Phee, Z. Sadouki, K. Kipper, A. A. Witney, N. Stoker, T. D. McHugh

This study investigates how concentration-dependent resistance emerges to isoniazid and rifampicin, showing that genotypic resistance only appears when antibiotic levels fall below MIC, and that isoniazid resistance involves concentration-dependent SNP accumulation.

bioRxiv · Sep 2, 2022 · PreprintPharmacology & Toxicology