Genetic modification of primary human B cells generates translationally-relevant models of high-grade lymphoma
R. Caeser, M. Di Re, J. A. Krupka, J. Gao, M. Lara-Chica, J. M. L. Dias, S. L. Cooke, R. Fenner, Z. Usheva, H. Runge, P. A. Beer, H. Eldaly, H.-K. Pak, C.-S. Park, G. Vassiliou, , D. J. Hodson
This study generates synthetic lymphoma models by genetically modifying primary human B cells to investigate oncogenic mutations in DLBCL.
bioRxiv · Apr 26, 2019 · PreprintCancer Biology