Remodeling and compaction of the inactive X is regulated by Xist during female B cell activation
Isabel Sierra, Son C. Nguyen, R. Jordan Barnett, Ashley L. Cook, Han-Seul Ryu, Zachary T. Beethem, Jennifer E. Phillips‐Cremins, Eric F. Joyce, Montserrat C. Anguera
This study shows that Xist regulates Xi compaction and TAD boundaries in B cells, impacting XCI maintenance and X-linked gene expression.
bioRxiv · Oct 19, 2022 · PreprintGenetics