Montserrat C. Anguera

This study shows that deleting Xist in B cells of female mice leads to SLE-like symptoms, suggesting XCI impairment contributes to the female bias in SLE.

The paper identifies sex-associated immune cell signatures in systemic sclerosis patients using high-dimensional immune profiling of peripheral blood mononuclear cells.

The paper investigates Xist RNA's role in X chromosome inactivation dynamics in B cells, finding Xist-dependent and independent epigenetic mechanisms that maintain XCI memory.

The paper investigates Xist RNA localization patterns in female progenitor cells from different tissues, showing tissue-specific and NF-kappaB-independent mechanisms of X chromosome inactivation.

This study investigates how B cell stimulation affects the structure and organization of the inactive X chromosome, revealing dynamic changes in TAD boundaries and Xi compaction.

The paper develops a 30-color immunophenotyping panel to identify and sort immune cell subsets in autoimmune diseases using minimal samples and high resolution.

This study shows that NF-κB signaling is necessary for maintaining X-chromosome inactivation in female T cells after activation.

This study uses scRNA-seq to analyze sex-based differences in neonatal lung injury recovery in mice, identifying transcriptional changes and cell-cell communication patterns influenced by biological sex.

This study shows that Xist regulates Xi compaction and TAD boundaries in B cells, impacting XCI maintenance and X-linked gene expression.