Author
University of PennsylvaniaORCID 0000-0002-7540-833XUnclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
5 papers
Recent·Most cited
Job Dekker, Betül Akgöl Oksuz, Yang Zhang…·Feng Yue
The paper integrates 4D Nucleome data to analyze 3D genome structure and function in human cells, revealing chromatin domains, loops, and interactions, and showing how genetic variants affect genome folding.
Isabel Sierra, Natalie E. Toothacre, Robin H. van der Weide…·Montserrat C. Anguera
This study investigates how B cell stimulation affects the structure and organization of the inactive X chromosome, revealing dynamic changes in TAD boundaries and Xi compaction.
Daniel S. Park, Son C. Nguyen, Randi L Isenhart…·Eric F. Joyce
The paper develops HiDRO, a high-throughput imaging pipeline, to screen the human druggable genome and identifies >300 factors regulating chromatin folding, including GSK3A as a regulator of TAD interactions.
Isabel Sierra, Son C. Nguyen, R. Jordan Barnett…·Montserrat C. Anguera
This study shows that Xist regulates Xi compaction and TAD boundaries in B cells, impacting XCI maintenance and X-linked gene expression.
Daniel J. Emerson, Peiyao A Zhao, Ashley L. Cook…·Jennifer E. Phillips‐Cremins
This study shows that cohesin-mediated loops in G1 phase determine the genomic location of replication origins in S phase by anchoring replication initiation zones.