Development of an Antiepileptogenesis Drug Screening Platform: Effects of Everolimus and Phenobarbital
Melissa L. Barker‐Haliski, Kevin M. Knox, Dannielle K. Zierath, Zachery Koneval, Cameron S. Metcalf, Karen S. Wilcox, H. Steve White
This paper describes a moderate-throughput drug screening platform in a rat model of temporal lobe epilepsy to evaluate antiepileptogenic agents, finding no significant effect of everolimus or phenobarbital on preventing spontaneous recurrent seizures.
Epilepsia · Jun 2, 2021Peer-reviewedNeuroscience