H. Steve White

The paper introduces a framework to evaluate preclinical seizure models' predictive validity for clinical focal onset seizures and identifies three models with high predictive validity.

This study examines the acute dose-related effects of antiseizure medicines on behavior in rats with epilepsy, finding varying impacts on locomotion and exploration.

This study examines how diet and sterilization affect gut microbiome diversity and acute seizure incidence in TMEV-infected mice, finding diet impacts seizure frequency and behavioral outcomes.

This paper introduces a novel mouse model of sustained seizure emergency with distinct pharmacological, electrographic, and pathological features compared to status epilepticus.

This paper describes a moderate-throughput drug screening platform in a rat model of temporal lobe epilepsy to evaluate antiepileptogenic agents, finding no significant effect of everolimus or phenobarbital on preventing spontaneous recurrent seizures.