16S ribosomal RNA modification drives transcript-specific translation efficiency
Zachory M. Park, Christina R. Savage, Amanda R. Decker-Farrell, Chin‐Hsien Tai, Tapan K. Maity, Weiming Yang, Lisa M. Miller Jenkins, Kumaran S. Ramamurthi
This study shows that 16S rRNA modification by MraW enhances translation efficiency, particularly for structured mRNAs, and that mRNA stem-loops regulate protein levels through ribosome modification.
Cell Reports · Aug 22, 2026Peer-reviewedMicrobiology