Author

Amanda R. Decker-Farrell

Cold Spring Harbor LaboratoryORCID 0000-0001-9969-7909Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Carmine F. PalermoiD· 1 shared Chin‐Hsien TaiiD· 1 shared Christina R. Savage· 1 shared Edward R. BallisteriD· 1 shared Kenneth P. OliveiD· 1 shared Kumaran S. RamamurthiiD· 1 shared Lisa M. Miller JenkinsiD· 1 shared Marie C. HasselluhniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Carmine F. PalermoORCID

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2 papers

Recent·Most cited

16S ribosomal RNA modification drives transcript-specific translation efficiency

Zachory M. Park, Christina R. Savage, Amanda R. Decker-Farrell, Chin‐Hsien Tai, Tapan K. Maity, Weiming Yang, Lisa M. Miller Jenkins, Kumaran S. Ramamurthi

This study shows that 16S rRNA modification by MraW enhances translation efficiency, particularly for structured mRNAs, and that mRNA stem-loops regulate protein levels through ribosome modification.

Cell Reports · Aug 22, 2026Peer-reviewedMicrobiology

Tumor-selective treatment of metastatic pancreatic cancer with an engineered, probiotic living drug

Amanda R. Decker-Farrell, Stephen A. Sastra, Tetsuhiro Harimoto, Marie C. Hasselluhn, Carmine F. Palermo, Edward R. Ballister, Michael A. Badgley, Tal Danino, Kenneth P. Olive

This study engineers a probiotic bacteria to selectively target pancreatic cancer, improving survival and modulating the tumor microenvironment.

bioRxiv · May 2, 2024 · PreprintCancer Biology