Compartment-Specific Neurexin Nanodomains Orchestrate Tripartite Synapse Assembly
Justin H. Trotter, Zahra Dargaei, Alessandra Sclip, Sofia Essayan-Perez, Kifayathullah Liakath‐Ali, Karthik Raju, Amber Nabet, Xinran Liu, Markus Wöhr, Thomas Christian Südhof
This study shows that neurexin-1 in astrocytes and neurons forms distinct nanodomains at synapses, enabling compartment-specific signaling that differentially regulates synapse function.
bioRxiv · Aug 21, 2020 · PreprintNeuroscience