Neddylation regulates the development and function of excitatory neurons
Josefa Torres, Zehra Vural, Maksims Fiošins, Fritz Benseler, Stefan Bonn, Silvio O. Rizzoli, JeongSeop Rhee, Nils Brose, Marilyn Tirard
This study shows that neddylation is essential for the development and function of glutamatergic neurons, with Nedd8 deletion causing defects in dendrite complexity and synaptic transmission.
bioRxiv · Dec 18, 2024 · PreprintNeuroscience