SARS-CoV-2 B Epitope-Guided Neoantigen NanoVaccines Enhance Tumor-Specific CD4/CD8 T Cell Immunity Through B Cell Antigen Presentation
Chengyi Li, Fang Ke, Shuai Mao, Zera Montemayor, Mohamed Dit Mady Traore, Alejandro Balsa, Mahamadou Djibo, Neha Karekar, Hongxiang Hu, Hanning Wen, Wei Gao, Duxin Sun
This study develops a neoantigen vaccine using SARS-CoV-2 B cell epitopes to enhance CD4/CD8 T cell immunity through B cell antigen presentation, showing improved efficacy in multiple cancer models.
ACS Nano · Feb 13, 2025Peer-reviewedImmunology