Duxin Sun

This study identifies Abi-1-S323 phosphorylation as a biomarker for DNA repair states and treatment response in cancers, showing its role in regulating radiosensitivity through Rac1 and CHK1 signaling.

This paper shows that an albumin-STING nanoagonist reprograms hematopoietic stem/progenitor cells into antitumor neutrophils, enhancing CD8+ T cell immunity against tumors.

This study develops a neoantigen vaccine using SARS-CoV-2 B cell epitopes to enhance CD4/CD8 T cell immunity through B cell antigen presentation, showing improved efficacy in multiple cancer models.

This paper introduces PROTAVs, a new vaccine strategy that enhances T cell responses and combination immunotherapy for melanoma by improving antigen processing and cross-presentation.

This paper develops a dual-targeting compound that eliminates regulatory B cells and overcomes STING resistance in pancreatic cancer, improving immunotherapy outcomes.