Author

Hanning Wen

University of Michigan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Duxin SuniD· 3 shared Bo WeniD· 2 shared Chengyi LiiD· 2 shared Fang KeiD· 2 shared Wei GaoiD· 2 shared Alejandro BalsaiD· 1 shared Chunpeng Yang· 1 shared Furong ChengiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersImmunology

Duxin SunORCID

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Author profile →

3 papers

Recent·Most cited

Albumin-STING Nanoagonist Reprograms HSPCs to Antitumor Neutrophils Enhancing MHC I-Mediated CD8+ T Cell Immunity

Jinsong Tao, Hongyi Zhao, Chengyi Li, Hanning Wen, Fang Ke, Qiuxia Li, Miao He, Bo Wen, Zhongwei Liu, Wei Gao, Duxin Sun

This paper shows that an albumin-STING nanoagonist reprograms hematopoietic stem/progenitor cells into antitumor neutrophils, enhancing CD8+ T cell immunity against tumors.

bioRxiv · Sep 2, 2025 · PreprintImmunology

SARS-CoV-2 B Epitope-Guided Neoantigen NanoVaccines Enhance Tumor-Specific CD4/CD8 T Cell Immunity Through B Cell Antigen Presentation

Chengyi Li, Fang Ke, Shuai Mao, Zera Montemayor, Mohamed Dit Mady Traore, Alejandro Balsa, Mahamadou Djibo, Neha Karekar, Hongxiang Hu, Hanning Wen, Wei Gao, Duxin Sun

This study develops a neoantigen vaccine using SARS-CoV-2 B cell epitopes to enhance CD4/CD8 T cell immunity through B cell antigen presentation, showing improved efficacy in multiple cancer models.

ACS Nano · Feb 13, 2025Peer-reviewedImmunology

Proteolysis-targeting vaccines (PROTAVs) for robust combination immunotherapy of melanoma

Qiyan Wang, Ting Su, Furong Cheng, Shurong Zhou, Xiang Liu, Mi Wang, You Xu, Ri Tang, Shimiao Liao, Jordan M. Dailey, Guolan Xiao, Chunpeng Yang, Hanning Wen, Weijia Zheng, Bo Wen, , Guizhi Zhu

This paper introduces PROTAVs, a new vaccine strategy that enhances T cell responses and combination immunotherapy for melanoma by improving antigen processing and cross-presentation.

bioRxiv · Oct 1, 2024 · PreprintBioengineering