Two-way feedback between chromatin compaction and histone modification state explains S. cerevisiae heterochromatin bistability
Ander Movilla Miangolarra, Daniel S. Saxton, Zhi Yan, Jasper Rine, Martin Howard
The paper develops a mathematical model showing bidirectional feedback between chromatin compaction and histone modifications explains bistability in S. cerevisiae heterochromatin.
Proceedings of the National Academy of Sciences · Apr 9, 2024Peer-reviewedSystems Biology