Author

Zhi-Hong Jiang

Macau University of Science and Technology

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Biology Disciplines

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Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Da Zhang· 1 shared Kai‐Yue CaoiD· 1 shared Long‐Bo Bai· 1 shared Rui‐Ze GongiD· 1 shared Tong‐Meng YaniD· 1 shared Yating ChengiD· 1 shared Yu PaniD· 1 shared Yu-Hang Zhang· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperGenetics

Da Zhang

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1 paper

Recent·Most cited

Targeted intervention of senescence induced by a 5' half fragment of tRNASec(NCA) with antisense oligonucleotide extends healthspan and lifespan in mice

Kai‐Yue Cao, Long‐Bo Bai, Da Zhang, Yu-Hang Zhang, Rui‐Ze Gong, Tong‐Meng Yan, Yu Pan, Yating Cheng, Zhi-Hong Jiang

This study identifies tRNASec(NCA) damage as an aging hallmark and shows that targeting its 5'-fragment with ASO extends healthspan and lifespan in mice.

bioRxiv · Mar 24, 2025 · PreprintGenetics