Gut microbial interaction networks control autoimmunity to neuroretina
Amy Zhang*, Reiko Horai, Yingyos Jittayasothorn, Jonathan H. Badger, Zhichao Wu, Guangpu Shi, Akriti Gupta, Samyuktha Arunkumar, Caitlin E. Murphy, Vijayaraj Nagarajan, John A. McCulloch, Shilpa Kodati, Hatice Nida Sen, Jung Wha Lee, Jonathan P. Jacobs, , Rachel R Caspi
Akkermansia expansion reduces short-chain fatty acid-producing Firmicutes in human-flora uveitis mice, raising Th1 responses and disease; a Verrucomicrobia/Firmicutes ratio is elevated in uveitis, MS and Crohn's patients.
bioRxiv · Oct 22, 2026 · PreprintImmunology✦ In-depth digest