Caitlin E. Murphy

Akkermansia expansion reduces short-chain fatty acid-producing Firmicutes in human-flora uveitis mice, raising Th1 responses and disease; a Verrucomicrobia/Firmicutes ratio is elevated in uveitis, MS and Crohn's patients.

This study investigates microbial dysbiosis in children with cystic fibrosis, identifying glycerol as a driver of altered microbial competition and linking colibactin production to increased colorectal cancer risk.