Profilin promotes lamellipodium protrusion by tuning the antagonistic activities of CP and VASP
Yubo Tang, Matthias Schaks, Magdalena Miętkowska, Jonas Scholz, Ruth Benavente-Naranjo, Sarah Körber, Zhilun Li, Christopher R. Lambert, Theresia E. B. Stradal, Roger Karlsson, Peter Bieling, Jan Faix, Martin Falcke, Klemens Rottner
This study investigates how profilin regulates lamellipodium protrusion by modulating the interactions between the Arp2/3 complex, capping protein, and Ena/VASP proteins.
bioRxiv · Mar 26, 2025 · PreprintCell Biology