Arp2/3 complex-dependent actin remodeling is required for efficient RSV uncoating in A549 cells
Enyu Xie, Maren Schubert, Jennifer M. Fricke, Benedikt Seligmann, Matthias Schaks, Mathias Müsken, Anika Steffen, Theresia E. B. Stradal, Sibylle Haid, Klemens Rottner, Christian Sieben
This study shows that Arp2/3 complex-dependent actin remodeling is necessary for efficient RSV uncoating in A549 cells, as Arp2 knockout cells exhibit reduced infection and viral mRNA expression.
Journal of Virology · Aug 31, 2026Peer-reviewedMicrobiology