Jan Faix

The paper identifies Y16 phosphorylation as a conserved switch controlling Ena/VASP recruitment to actin assembly sites, using cell-based reconstitution and biochemical assays.

This study identifies IqgD as a Rac1-interacting IQGAP in Dictyostelium discoideum essential for efficient phagocytosis of surface-bound bacteria.

This study shows cytochalasin B differentially affects barbed end-binding proteins in lamellipodia, enhancing rather than inhibiting their accumulation and interactions.

This study shows that the fibrocystin C-terminal domain suppresses Src/STAT3 signaling, preventing cyst formation in kidney epithelial cells by inhibiting secretory phenotype and STAT3-dependent transcription.

This study investigates how profilin regulates lamellipodium protrusion by modulating the interactions between the Arp2/3 complex, capping protein, and Ena/VASP proteins.