Author

Zhipeng Fang

City Of Hope National Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1 Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1

Frequent Co-Authors

David HorneiD· 2 shared Wendong HuangiD· 2 shared Adolfo Garcı́a-OcañaiD· 1 shared Alon Agua· 1 shared Alon Roy L. Agua· 1 shared Holly Yin· 1 shared J. Jefferson P. Perry· 1 shared Jemima Pangemanan· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersPharmacology & Toxicology

David HorneORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Development of CYP8B1-specific inhibitors for metabolic diseases

Zhipeng Fang, Alon Roy L. Agua, Jennifer Jossart, Nisha Sharma, Xintian Lyu, Zhe Wang, Shili Zhang, Ji Sun, Linsen Shi, Juan Ayard, Maggie Chang, Jiahui Liu, Kevin Kou, John Shively, Adolfo Garcı́a-Ocaña, , Wendong Huang

This study develops CYP8B1-specific inhibitors that alter bile acid composition, remodel gut microbiota, and improve metabolic disease in a mouse model.

bioRxiv · Oct 22, 2026 · PreprintPharmacology & Toxicology

MXRA7 Alleviates Epididymitis from Exercise-Induced Fatigue by Inhibiting Pyroptosis

Kun-Yang Tang, Xiaocui Jiang, ZhiPeng FANG, Xin Hu, JiaSen LIU, Yu Xi, Min ZHAO, Ying Liu, JiGang CAO, Yanyan Zhou, Min XIAO

This study investigates how exercise-induced fatigue affects the male reproductive system and shows that MXRA7 reduces epididymitis by inhibiting pyroptosis.

bioRxiv · Feb 13, 2026 · PreprintMolecular Biology

Novel circadian clock activators display anti-obesity efficacy via suppression of adipocyte development and hypertrophy

Xuekai Xiong, Jemima Pangemanan, Tali Kiperman, Lu Tang, Zhipeng Fang, Alon Agua, Wendong Huang, David Horne, Ke Ma

This paper identifies novel clock activators, chlorhexidine and CM002, that suppress adipocyte development and hypertrophy, leading to anti-obesity effects in mice.

bioRxiv · Jan 9, 2026 · PreprintPhysiology