Novel circadian clock activators display anti-obesity efficacy via suppression of adipocyte development and hypertrophy
Xuekai Xiong, Jemima Pangemanan, Tali Kiperman, Lu Tang, Zhipeng Fang, Alon Agua, Wendong Huang, David Horne, Ke Ma
This paper identifies novel clock activators, chlorhexidine and CM002, that suppress adipocyte development and hypertrophy, leading to anti-obesity effects in mice.
bioRxiv · Jan 9, 2026 · PreprintPhysiology