Author

Zhixian He

The Ohio State University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Dawei ZhouiD· 2 shared Guillaume N. FichesiD· 2 shared Jianwen CheniD· 2 shared Jinshan HeiD· 2 shared K.A.S.N. ShanakaiD· 2 shared Netty G. SantosoiD· 2 shared Thurbu Tshering Lepcha· 2 shared Youngmin ParkiD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersMicrobiology

Dawei ZhouORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

m5C RNA Methylation Is Dysregulated by Oncogenic Herpesviruses via c-Myc Signaling to Counteract Host Antiviral Factors

Zhenyu Wu, Yan Liu, Dawei Zhou, Zhixian He, Guillaume N. Fiches, Youngmin Park, Alan Zhu, Jinshan He, Jianwen Chen, K.A.S.N. Shanaka, Thurbu Tshering Lepcha, Prashant Desai, Jian Kang Zhu, Netty G. Santoso

This study shows that KSHV and EBV reduce host m5C RNA methylation via c-Myc to destabilize TRIM25 and promote lytic replication.

Nucleic Acids Research · Mar 19, 2026Peer-reviewedMicrobiology

Analysis of Head and Neck Cancer scRNA-seq Data Identified PRDM6 Promotes Tumor Progression by Modulating Immune Gene Expression

Zhenyu Wu, Thurbu Tshering Lepcha, Dawei Zhou, Zhixian He, Guillaume N. Fiches, Youngmin Park, Jinshan He, Jianwen Chen, K.A.S.N. Shanaka, Steve Oghumu, Weiqiang Zhao, Anjun Ma, Qin Ma, Jian Zhu, Netty G. Santoso

The paper identifies PRDM6 as a promoter of tumor progression in HNSCC by modulating immune gene expression using scRNA-seq data and IRIS3 analysis.

Frontiers in Immunology · Aug 27, 2025Peer-reviewedCancer Biology