Author

Zhenyu Wu

The Ohio State UniversityORCID 0000-0002-1123-4705Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Zhenyu Wu2 papers · King Abdullah University of Science and Technology

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

Dawei ZhouiD· 2 shared Guillaume N. FichesiD· 2 shared Jinshan HeiD· 2 shared K.A.S.N. ShanakaiD· 2 shared Netty G. SantosoiD· 2 shared Thurbu Tshering Lepcha· 2 shared Youngmin ParkiD· 2 shared Alan Zhu· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersMicrobiology

Dawei ZhouORCID

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2 papers

Recent·Most cited

Microbiologynpj VirusesPeer-reviewedAug 22, 2026

Inhibition of KDM5A/B promotes antitumor innate immune responses in HHV-8/KSHV-positive B-cell lymphomas

Dawei Zhou, Guillaume N. Fiches, Zhenyu Wu…·Netty G. Santoso

This study shows that inhibiting KDM5A/B enhances antitumor innate immune responses and induces KSHV lytic reactivation in KSHV-positive B-cell lymphomas.

DOI 10.1038/s44298-026-00223-3

humanDNA methylation

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MicrobiologyNucleic Acids ResearchPeer-reviewedMar 19, 2026

m5C RNA Methylation Is Dysregulated by Oncogenic Herpesviruses via c-Myc Signaling to Counteract Host Antiviral Factors

Zhenyu Wu, Yan Liu, Dawei Zhou…·Netty G. Santoso

This study shows that KSHV and EBV reduce host m5C RNA methylation via c-Myc to destabilize TRIM25 and promote lytic replication.

2 citationstop 4%

humanbulk RNA-seq

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