Author

Zhong Chen

Loma Linda University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:rat· 2 Assay:snRNA-seq· 2 Approach:statistical model· 2 Research Focus:database / resource· 1 Assay:metabolomics· 1

Frequent Co-Authors

Charles WangiD· 3 shared Wanqiu CheniD· 3 shared Yan DongiD· 3 shared Wendell Jones· 2 shared Alexander K. ZinsmaieriD· 1 shared Chirag NepaliD· 1 shared Daliao XiaoiD· 1 shared Eric J. NestleriD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersNeuroscience

Charles WangORCID

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Author profile →

3 papers

Recent·Most cited

Prenatal e-cigarette exposure induces region- and cell type-specific metabolic and developmental reprogramming

Wanqiu Chen, Zhong Chen, Chirag Nepal, Xue Pan, Wei-Xing Shi, Yong Li, Daliao Xiao, Wendell Jones, Malcolm Moos, Yan Dong, Charles Wang

This study shows prenatal e-cigarette exposure causes region- and cell type-specific metabolic and developmental changes in neonatal rat brains, linked to neurodevelopmental disease risk.

bioRxiv · Jun 24, 2026 · PreprintNeuroscience

Prenatal THC exposure disrupts mitochondrial respiratory gene programs and medium spiny neuron maturation trajectories in the nucleus accumbens

Zhong Chen, Wanqiu Chen, Yun Seok Lee, Wendell Jones, Laura M. Goetzl, Jennifer Dawn Thomas, Yan Dong, Charles Wang

This study shows that prenatal THC exposure disrupts mitochondrial gene programs and medium spiny neuron maturation in the nucleus accumbens using snRNA-seq and snATAC-seq in a rat model.

bioRxiv · Jun 19, 2026 · PreprintNeuroscience

Astrocytic D1 Dopamine-Signaling Regulates Synaptic Remodeling and Cocaine Seeking

Shi Yan, Qize Li, Yao Wang, Wanqiu Chen, Zhong Chen, Alexander K. Zinsmaier, Paloma Renata Huguet Rodriguez, Zhengsong Lu, Xiguang Qi, Zheng Xu, Yi Han, Gouri Sharma, Charles Wang, Eric J. Nestler, Oliver M. Schlüter, Yan Dong

This study shows that astrocytic D1 dopamine receptors in the nucleus accumbens shell regulate synaptic remodeling and cocaine seeking behavior in mice.

bioRxiv · May 18, 2026 · PreprintNeuroscience