KIDINS220 and InsP8 safeguard the stepwise regulation of phosphate exporter XPR1
Xiaojie Wang, Zhongjian Bai, Ciara Wallis, Huanchen Wang, Yaoyao Han, Ruitao Jin, Mingguang Lei, Tian Yang, Chunfang Gu, Henning Jacob Jessen, Stephen B. Shears, Yadong Sun, Ben Corry, Yixiao Zhang
This study reveals how KIDINS220 and InsP8 regulate XPR1's phosphate export through structural mechanisms and evolutionary insights.
Molecular Cell · Aug 25, 2025Peer-reviewedMolecular Biology